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Anti-EGFR Antibody (1M293) (Synonyms: PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor rece...)

Catalog No. TMAY-00021 Copy Product Info
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Anti-EGFR Antibody (1M293) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (1M293) can be used in ELISA.

Anti-EGFR Antibody (1M293)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00021
Synonyms PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor

Anti-EGFR Antibody (1M293) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (1M293) can be used in ELISA.

Anti-EGFR Antibody
(1M293)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-EGFR Antibody (1M293) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (1M293) can be used in ELISA.
SynonymsPIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Ig Type
Mouse IgG2b
Clone
1M293
Reactivity
Human
Specificity
Human EGFR
No cross-reactivity in ELISA with
Human EGFR/ErbB1
Human ErbB2
Human ErbB3
Human ErbB4
Human cell lysate (293 cell line)
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EGFR / ErbB / HER1 (rh EGFR / ErbB / HER1; Catalog #10001-H08H; Met 1-Ser 645; NP_005219). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAs a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human EGFR / ErbB / HER1 Protein (TMPY-00742)
Antigen Species
Human
Biology Area
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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