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Anti-CCL28 Antibody (3W134)

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Catalog No. TMAY-01034

Anti-CCL28 Antibody (3W134) is a Mouse antibody targeting CCL28. Anti-CCL28 Antibody (3W134) can be used in ELISA.

Anti-CCL28 Antibody (3W134)

Anti-CCL28 Antibody (3W134)

😃Good
Catalog No. TMAY-01034
Anti-CCL28 Antibody (3W134) is a Mouse antibody targeting CCL28. Anti-CCL28 Antibody (3W134) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
20 μL$70 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CCL28 Antibody (3W134) is a Mouse antibody targeting CCL28. Anti-CCL28 Antibody (3W134) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
Clone
3W134
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CCL28 / SCYA28 (rh CCL28 / SCYA28; TMPY-03728; NP_683513.1; Ile23-Tyr127). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and lactating mammary gland as well. Besides, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues and secretions suggest that this protein plays an important role in innate immune protection of the epithelial surfaces. CCL28 is a human chemokine constitutively expressed by epithelial cells in diverse mucosal tissues and is known to attract a variety of immune cell types including T-cell subsets and eosinophils. Elevated levels of CCL28 have been found in the airways of individuals with asthma, and previous studies have indicated that CCL28 plays a vital role in the acute development of post-viral asthma. CCL28 presents a novel target for the development of alternative asthma therapeutics. The dental decay of children leads to the secretion of chemokine CCL28, which promotes the secretion of sIgA in saliva. CC chemokine ligand28 (CCL28) has been reported as a severity marker in atopic dermatitis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CCL28 / SCYA28 Protein (TMPY-03728)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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