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Bcl-B inhibitor 1

Name: Bcl-B inhibitor 1
Brand: TargetMol
SKU: T77571
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T77571Cas No. 79220-88-5

Bcl-B inhibitor 1 is an antitumor compound that binds to and inactivates pro-apoptotic proteins in the BH3 structural domain.

Bcl-B inhibitor 1

🥰Excellent

Purity: 97.77%

Catalog No. T77571Cas No. 79220-88-5

Bcl-B inhibitor 1 is an antitumor compound that binds to and inactivates pro-apoptotic proteins in the BH3 structural domain.

Pack Size	Price	Availability
10 mg	$31	In Stock
25 mg	$50	In Stock
50 mg	$68	In Stock
100 mg	$107	In Stock

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Batch Information

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Purity:97.77%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

Bcl-B inhibitor 1 is an antitumor compound that binds to and inactivates pro-apoptotic proteins in the BH3 structural domain.

Chemical Properties

Molecular Weight	309.39
Formula	C₁₇H₁₅N₃OS
Cas No.	79220-88-5
Smiles	S=C1N(C=C(N1)C2=CC=CC=C2)C3=CC=C(NC(C)=O)C=C3
Relative Density.	1.34 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (145.45 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2322 mL	16.1608 mL	32.3217 mL	161.6083 mL
5 mM	0.6464 mL	3.2322 mL	6.4643 mL	32.3217 mL
10 mM	0.3232 mL	1.6161 mL	3.2322 mL	16.1608 mL
20 mM	0.1616 mL	0.8080 mL	1.6161 mL	8.0804 mL
50 mM	0.0646 mL	0.3232 mL	0.6464 mL	3.2322 mL
100 mM	0.0323 mL	0.1616 mL	0.3232 mL	1.6161 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc