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Clindamycin hydrochloride monohydrate (Synonyms: Clindamycin alcoholate)

Name: Clindamycin hydrochloride monohydrate
Brand: TargetMol
SKU: T22297
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T22297 Copy Product Info

Purity: 99.80%

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Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentrations (sub-MICs). It acts by suppressing Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla) production. Resistance to this compound emerges through enzymatic methylation at the antibiotic's 50S ribosomal subunit binding site (23S rRNA).

Clindamycin hydrochloride monohydrate

Copy Product Info

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Catalog No. T22297

Synonyms Clindamycin alcoholate

Cas No. 58207-19-5

Pack Size	Price	USA Stock	Global Stock
100 mg	$32	-	In Stock
200 mg	$45	-	In Stock
500 mg	$72	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.80%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Synonyms

Clindamycin alcoholate

Chemical Properties

Molecular Weight	479.46
Formula	C₁₈H₃₆Cl₂N₂O₆S
Cas No.	58207-19-5
Smiles	O.Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (187.71 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0857 mL	10.4284 mL	20.8568 mL	104.2840 mL
5 mM	0.4171 mL	2.0857 mL	4.1714 mL	20.8568 mL
10 mM	0.2086 mL	1.0428 mL	2.0857 mL	10.4284 mL
20 mM	0.1043 mL	0.5214 mL	1.0428 mL	5.2142 mL
50 mM	0.0417 mL	0.2086 mL	0.4171 mL	2.0857 mL
100 mM	0.0209 mL	0.1043 mL	0.2086 mL	1.0428 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Clindamycin hydrochloride MonohydrateClindamycin HydrochlorideAntibiotic

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