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STING ligand-1

Name: STING ligand-1
Brand: TargetMol
SKU: T13906
Price: 392 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13906Cas No. 2365039-41-2

STING ligand-1 is a lead stimulator of the STING pathway with an IC₅₀ of 68 nM for HAQ STING, STING ligand-1 I shows potential in research related to inflammation and immunology.

STING ligand-1

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Purity: 98.83%

Catalog No. T13906Cas No. 2365039-41-2

STING ligand-1 is a lead stimulator of the STING pathway with an IC₅₀ of 68 nM for HAQ STING, STING ligand-1 I shows potential in research related to inflammation and immunology.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$392	-	In Stock
5 mg	$935	-	In Stock
10 mg	$1,270	-	In Stock
25 mg	$1,890	-	In Stock
50 mg	$2,990	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.83%

ee:100%

Resource Download

COA HNMR LCMS ORP CSFC FNMR

Product Introduction

Bioactivity

Description	STING ligand-1 is a lead stimulator of the STING pathway with an IC₅₀ of 68 nM for HAQ STING, STING ligand-1 I shows potential in research related to inflammation and immunology.
Targets&IC50	HAQ STING:68 nM
In vitro	STING ligand-1 exhibits good oral exposure, slow binding kinetics, and functional inhibition of STING-mediated cytokine release [1].

Chemical Properties

Molecular Weight	523.98
Formula	C₂₉H₂₇ClFNO₅
Cas No.	2365039-41-2
Smiles	C(C(O)=O)[C@@H]1[C@H](N(C(=O)C=2C1=CC=C(F)C2)C3=CC(Cl)=C(C(C)(C)C)C=C3)C=4C=C5C(=CC4)OCCO5
Relative Density.	1.322 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (152.68 mM), Sonication is recommeded.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9085 mL	9.5423 mL	19.0847 mL	95.4235 mL
5 mM	0.3817 mL	1.9085 mL	3.8169 mL	19.0847 mL
10 mM	0.1908 mL	0.9542 mL	1.9085 mL	9.5423 mL
20 mM	0.0954 mL	0.4771 mL	0.9542 mL	4.7712 mL
50 mM	0.0382 mL	0.1908 mL	0.3817 mL	1.9085 mL
100 mM	0.0191 mL	0.0954 mL	0.1908 mL	0.9542 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc