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Beauveriolide III, a cyclodepsipeptide found in Beauveria fungi, inhibits lipid droplet formation (at 3-10 μM) and cholesterol synthesis (IC50=0.41 μM). This compound also suppresses acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity (IC50=5.5 μM) and reduces atherosclerotic lesion size in Ldlr-/- and ApoE-/- mouse models (25-50 mg/kg).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $817 | In Stock | |
5 mg | $1,686 | In Stock | |
10 mg | $2,270 | In Stock | |
25 mg | $3,370 | In Stock | |
50 mg | $4,550 | In Stock |
Description | Beauveriolide III, a cyclodepsipeptide found in Beauveria fungi, inhibits lipid droplet formation (at 3-10 μM) and cholesterol synthesis (IC50=0.41 μM). This compound also suppresses acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity (IC50=5.5 μM) and reduces atherosclerotic lesion size in Ldlr-/- and ApoE-/- mouse models (25-50 mg/kg). |
Synonyms | BeauveriolideIII |
Molecular Weight | 487.63 |
Formula | C27H41N3O5 |
Cas No. | 221111-70-2 |
Smiles | C([C@@H]1NC(=O)C[C@@]([C@H](CCCC)C)(OC(=O)[C@@]([C@H](CC)C)(NC(=O)[C@H](C)NC1=O)[H])[H])C2=CC=CC=C2 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | Methanol: Soluble, Sonication is recommended. DMSO: Soluble, Sonication is recommended. |
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