Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact UsQuotation
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

Maurocalcine

😃Good
Catalog No. T80153Cas No. 269745-22-4

Maurocalcine is a cell-permeable agonist for ryanodine receptor (RyR) subtypes 1, 2, and 3. It enhances [3 H]ryanodine binding to RyR1 with an EC50 of 2558 nM and demonstrates an apparent affinity for RyR2 at 14 nM. This compound is suitable for in vivo cell tracking and other cellular imaging applications [1] [2] [3].

Maurocalcine
Other Forms of Maurocalcine:
Maurocalcine TFATP2868
Backorder
View details

Maurocalcine

😃Good
Catalog No. T80153Cas No. 269745-22-4
Maurocalcine is a cell-permeable agonist for ryanodine receptor (RyR) subtypes 1, 2, and 3. It enhances [3 H]ryanodine binding to RyR1 with an EC50 of 2558 nM and demonstrates an apparent affinity for RyR2 at 14 nM. This compound is suitable for in vivo cell tracking and other cellular imaging applications [1] [2] [3].
Pack SizePriceAvailabilityQuantity
5 mgInquiryBackorder
50 mgInquiryBackorder
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Resource Download

Product Introduction

Bioactivity
Description
Maurocalcine is a cell-permeable agonist for ryanodine receptor (RyR) subtypes 1, 2, and 3. It enhances [3 H]ryanodine binding to RyR1 with an EC50 of 2558 nM and demonstrates an apparent affinity for RyR2 at 14 nM. This compound is suitable for in vivo cell tracking and other cellular imaging applications [1] [2] [3].
In vitro
Maurocalcine (100 nM, 24 hours) enhances the sensitivity of RyR2 to activating [Ca2+]i while diminishing its sensitivity to inhibitory [Ca2+]i [1]. There is no cytotoxicity observed in HEK293 cells when treated with Maurocalcine (5 μM for 4 hours/24 hours) [3].
Chemical Properties
Molecular Weight3858.55
FormulaC156H270N56O46S6
Cas No.269745-22-4
SequenceGly-Asp-Cys-Leu-Pro-His-Leu-Lys-Leu-Cys-Lys-Glu-Asn-Lys-Asp-Cys-Cys-Ser-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ile-Glu-Lys-Arg-Cys-Arg (Disulfide bridge:Cys3-Cys17;Cys10-Cys21;Cys16-Cys32)
Sequence ShortGDCLPHLKLCKENKDCCSKKCKRRGTNIEKRCR (Disulfide bridge:Cys3-Cys17;Cys10-Cys21;Cys16-Cys32)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CalciumChannelCalcium Channel
Related Tags: buy Maurocalcine | purchase Maurocalcine | Maurocalcine cost | order Maurocalcine | Maurocalcine in vitro | Maurocalcine formula | Maurocalcine molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.