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Anti-Ficolin 1/FCN1 Antibody (2J391)
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Catalog No. TMAY-01345
Alias ficolin 1, FCNA, FCN1
Anti-Ficolin 1/FCN1 Antibody (2J391) is a Rabbit antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (2J391) can be used in ELISA.
Anti-Ficolin 1/FCN1 Antibody (2J391)
Anti-Ficolin 1/FCN1 Antibody (2J391)
😃Good
Catalog No. TMAY-01345Alias ficolin 1, FCNA, FCN1
Anti-Ficolin 1/FCN1 Antibody (2J391) is a Rabbit antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (2J391) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | ficolin 1, FCNA, FCN1 |
| Ig Type | Rabbit IgG |
| Clone | 2J391 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human FCN1 (rh FCN1; TMPY-01028; NP_001994.2; Met 1-Ala 326). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. Three Ficolins have been identified in humans: L-Ficolin, H-Ficolin and M-Ficolin (also referred to as Ficolin-2, -3 and -1, respectively). They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Dysfunction or abnormal expressions of Ficolins may involved in the pathogenesis of human diseases including infectious and inflammatory diseases, autoimmune disease and clinical syndrome of preeclampsia. They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Upon recognition of the infectious agent, the Ficolins act through two distinct routes: initiate the lectin pathway of complement activation through attached serine proteases (MASPs), and a primitive opsonophagocytosis thus limiting the infection and concurrently orchestrating the subsequent adaptive clonal immune response. Ficolin-1 (FCN1) is predominantly expressed in the peripheral blood leukocytes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human FCN1 protein (TMPY-01028) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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