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Moracin C

Name: Moracin C
Brand: TargetMol
SKU: TN1949
Price: 198 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1949Cas No. 69120-06-5

Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.

Moracin C

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Purity: 99.77%

Catalog No. TN1949Cas No. 69120-06-5

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$198	In Stock	In Stock
5 mg	$513	In Stock	In Stock
10 mg	$747	-	In Stock
25 mg	$1,160	-	In Stock
50 mg	$1,560	-	In Stock
100 mg	$2,080	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.77%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.
Targets&IC50	FabI (S. aureus):83.8 µM, S. aureus:32 µg/mL(MIC)
In vitro	Moracin C (1-50 μM, 24 h) inhibited the release of LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) from RAW264.7 cells.[2] Moracin C (1-50 μM, 2 h) inhibits mRNA and protein expression of iNOS and COX-2 in RAW264.7 cells.[2] Moracin C (1-50 μM, 2 h) inhibits the production of pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α) in LPS-activated RAW 264.7 cells [1]. Moracin C (1-50 μM, 2 h) inhibits the phosphorylation of p38, ERK and JNK in LPS-activated RAW 264.7 cells.[2]
In vivo	Moracin C (100 mg/kg, gavage, mice) is rapidly and well absorbed in the intestinal tract and is widely distributed in the gastrointestinal tract, liver, kidney and lungs.[3]

Chemical Properties

Molecular Weight	310.34
Formula	C₁₉H₁₈O₄
Cas No.	69120-06-5
Smiles	CC(C)=CCc1c(O)cc(cc1O)-c1cc2ccc(O)cc2o1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 225 mg/mL (725.01 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 3.3 mg/mL (10.63 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2223 mL	16.1114 mL	32.2227 mL	161.1136 mL
5 mM	0.6445 mL	3.2223 mL	6.4445 mL	32.2227 mL
10 mM	0.3222 mL	1.6111 mL	3.2223 mL	16.1114 mL
20 mM	0.1611 mL	0.8056 mL	1.6111 mL	8.0557 mL
50 mM	0.0644 mL	0.3222 mL	0.6445 mL	3.2223 mL
100 mM	0.0322 mL	0.1611 mL	0.3222 mL	1.6111 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc