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Moracin C

Name: Moracin C
Brand: TargetMol
SKU: TN1949
Price: 198 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. TN1949 Copy Product Info

Purity: 99.77%

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Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.

Moracin C

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Catalog No. TN1949

Cas No. 69120-06-5

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Pack Size	Price	USA Stock	Global Stock
1 mg	$198	In Stock	In Stock
5 mg	$513	In Stock	In Stock
10 mg	$747	-	In Stock
25 mg	$1,160	-	In Stock
50 mg	$1,560	4-6 weeks	4-6 weeks
100 mg	$2,080	4-6 weeks	4-6 weeks

In stock · Dispatch: USA[1-2d] Global[5-7d]

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.77%

Appearance:Solid

Color:Yellow

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.
Targets&IC50	S. aureus:32 µg/mL(MIC), FabI (S. aureus):83.8 µM
In vitro	Moracin C (1-50 μM, 24 h) inhibited the release of LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) from RAW264.7 cells.[2] Moracin C (1-50 μM, 2 h) inhibits mRNA and protein expression of iNOS and COX-2 in RAW264.7 cells.[2] Moracin C (1-50 μM, 2 h) inhibits the production of pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α) in LPS-activated RAW 264.7 cells [1]. Moracin C (1-50 μM, 2 h) inhibits the phosphorylation of p38, ERK and JNK in LPS-activated RAW 264.7 cells.[2]
In vivo	Moracin C (100 mg/kg, gavage, mice) is rapidly and well absorbed in the intestinal tract and is widely distributed in the gastrointestinal tract, liver, kidney and lungs.[3]

Chemical Properties

Molecular Weight	310.34
Formula	C₁₉H₁₈O₄
Cas No.	69120-06-5
Smiles	CC(C)=CCc1c(O)cc(cc1O)-c1cc2ccc(O)cc2o1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 225 mg/mL (725.01 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 3.3 mg/mL (10.63 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2223 mL	16.1114 mL	32.2227 mL	161.1136 mL
5 mM	0.6445 mL	3.2223 mL	6.4445 mL	32.2227 mL
10 mM	0.3222 mL	1.6111 mL	3.2223 mL	16.1114 mL
20 mM	0.1611 mL	0.8056 mL	1.6111 mL	8.0557 mL
50 mM	0.0644 mL	0.3222 mL	0.6445 mL	3.2223 mL
100 mM	0.0322 mL	0.1611 mL	0.3222 mL	1.6111 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc