keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.1/β1, Nav1.2/β1, Nav1.4/β1, and Nav1.5/β1 with IC50 values of 523 nM, 3 nM, 888 nM, and 323 nM, respectively. Additionally, Ceratotoxin-1 is known to inhibit Nav1.8/β1 [1].
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Description | Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.1/β1, Nav1.2/β1, Nav1.4/β1, and Nav1.5/β1 with IC50 values of 523 nM, 3 nM, 888 nM, and 323 nM, respectively. Additionally, Ceratotoxin-1 is known to inhibit Nav1.8/β1 [1]. |
Targets&IC50 | Nav1.4:888 nM, Nav1.1:523 nM, Nav1.2:3 nM, Nav1.5:323 nM |
Synonyms | CcoTx1, β-TRTX-cm1a |
Molecular Weight | 4044.58 |
Formula | C172H256N52O50S6 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Ceratotoxin-1 Membrane transporter/Ion channel Sodium Channel CcoTx1 β-TRTX-cm1a inhibitor inhibit