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Malonic acid

🥰Excellent
Catalog No. T5291Cas No. 141-82-2
Alias Propanedioic Acid, Carboxyacetic Acid, 1,3-Propanedioic Acid

Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism.

Malonic acid

Malonic acid

🥰Excellent
Purity: 99.53%
Catalog No. T5291Alias Propanedioic Acid, Carboxyacetic Acid, 1,3-Propanedioic AcidCas No. 141-82-2
Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism.
Pack SizePriceAvailabilityQuantity
25 mg$46In Stock
50 mg$66In Stock
100 mg$96In Stock
500 mg$138In Stock
1 g$209In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Purity:99.53%
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Product Introduction

Bioactivity
Description
Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism.
SynonymsPropanedioic Acid, Carboxyacetic Acid, 1,3-Propanedioic Acid
Chemical Properties
Molecular Weight104.06
FormulaC3H4O4
Cas No.141-82-2
SmilesOC(=O)CC(O)=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55.00 mg/mL (528.54 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM9.6098 mL48.0492 mL96.0984 mL480.4920 mL
5 mM1.9220 mL9.6098 mL19.2197 mL96.0984 mL
10 mM0.9610 mL4.8049 mL9.6098 mL48.0492 mL
20 mM0.4805 mL2.4025 mL4.8049 mL24.0246 mL
50 mM0.1922 mL0.9610 mL1.9220 mL9.6098 mL
100 mM0.0961 mL0.4805 mL0.9610 mL4.8049 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Malonic acid
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