Powder: -20°C for 3 years | In solvent: -80°C for 1 year
9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and IFN-γ-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells when used at a concentration of 5 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 83.00 | |
1 mg | 35 days | $ 158.00 | |
5 mg | 35 days | $ 490.00 |
Description | 9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and IFN-γ-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells when used at a concentration of 5 μM. |
Targets&IC50 | 15-LOX1:0.19 μM (IC50) |
Molecular Weight | 412.87 |
Formula | C22H21ClN2O4 |
CAS No. | 2349374-37-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methanol: Slightly soluble
DMSO: Soluble
You can also refer to dose conversion for different animals. More
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15-LOX-1 inhibitor 1 2349374-37-2 15 LOX 1 inhibitor 1 15LOX1 inhibitor 1 inhibitor inhibit