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Tregalizumab (Synonyms: BT-061, BT061)

Catalog No. T78291 Copy Product Info
Purity: 95%
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Tregalizumab (BT-061) is a humanised monoclonal antibody targeting CD4, capable of binding unique epitopes on CD4 and selectively inducing regulatory T cell (Treg) activation. It holds potential applications in immunology and inflammation.

Tregalizumab

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Catalog No. T78291
Synonyms BT-061, BT061

Tregalizumab (BT-061) is a humanised monoclonal antibody targeting CD4, capable of binding unique epitopes on CD4 and selectively inducing regulatory T cell (Treg) activation. It holds potential applications in immunology and inflammation.

Tregalizumab
Cas No. 1207446-68-1
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$745-In Stock
10 mg$1,180-In Stock
25 mg$1,770-In Stock
50 mg$2,380-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.0% (SDS-PAGE); 98.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Tregalizumab (BT-061) is a humanised monoclonal antibody targeting CD4, capable of binding unique epitopes on CD4 and selectively inducing regulatory T cell (Treg) activation. It holds potential applications in immunology and inflammation.
In vitro
Methods: Peripheral blood mononuclear cells (PBMCs) were treated with Tregalizumab (0-30 µg/mL for 18 hours), and the downregulation of CD4 expression was detected by flow cytometry.
Results: At a concentration of 10 μg/mL Tregalizumab, CD4 expression in T cells significantly decreased and reached a steady state within 18 hours.[2]
SynonymsBT-061, BT061
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD4/LEU3
Chemical Properties
Molecular Weight147.41 kDa
Cas No.1207446-68-1
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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