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Tregalizumab (Synonyms: BT-061, BT061)

Catalog No. T78291 Copy Product Info
Purity: 95%
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Tregalizumab (BT-061) is a humanised monoclonal antibody targeting CD4, capable of binding unique epitopes on CD4 and selectively inducing regulatory T cell (Treg) activation. It holds potential applications in immunology and inflammation.

Tregalizumab

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Catalog No. T78291
Synonyms BT-061, BT061

Tregalizumab (BT-061) is a humanised monoclonal antibody targeting CD4, capable of binding unique epitopes on CD4 and selectively inducing regulatory T cell (Treg) activation. It holds potential applications in immunology and inflammation.

Tregalizumab
Cas No. 1207446-68-1
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$745-In Stock
10 mg$1,180-In Stock
25 mg$1,770-In Stock
50 mg$2,380-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.0% (SDS-PAGE); 98.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Tregalizumab (BT-061) is a humanised monoclonal antibody targeting CD4, capable of binding unique epitopes on CD4 and selectively inducing regulatory T cell (Treg) activation. It holds potential applications in immunology and inflammation.
In vitro
Methods: Peripheral blood mononuclear cells (PBMCs) were treated with Tregalizumab (0-30 µg/mL for 18 hours), and the downregulation of CD4 expression was detected by flow cytometry.
Results: At a concentration of 10 μg/mL Tregalizumab, CD4 expression in T cells significantly decreased and reached a steady state within 18 hours.[2]
SynonymsBT-061, BT061
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD4/LEU3
Chemical Properties
Molecular Weight147.41 kDa
Cas No.1207446-68-1
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at -20°C Shipping with blue ice/Shipping at ambient temperature.

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