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Digitoxin

Name: Digitoxin
Brand: TargetMol
SKU: T0295
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0295Cas No. 71-63-6

Alias Unidigin, Digitoxoside, Digitoxinum

Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).

Digitoxin

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Purity: 98.54%

Catalog No. T0295Alias Unidigin, Digitoxoside, DigitoxinumCas No. 71-63-6

Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).

Pack Size	Price	Availability
5 mg	$29	In Stock
10 mg	$30	In Stock
25 mg	$41	In Stock
50 mg	$58	In Stock
1 mL x 10 mM (in DMSO)	$31	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.54%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).
Targets&IC50	Na+, K+-ATPase:0.78 μM(EC50)
Synonyms	Unidigin, Digitoxoside, Digitoxinum

Chemical Properties

Molecular Weight	764.94
Formula	C₄₁H₆₄O₁₃
Cas No.	71-63-6
Smiles	C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4CC[C@]4(C)[C@H](CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C
Relative Density.	1.33 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (130.73 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (5.23 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3073 mL	6.5365 mL	13.0729 mL	65.3646 mL
5 mM	0.2615 mL	1.3073 mL	2.6146 mL	13.0729 mL
10 mM	0.1307 mL	0.6536 mL	1.3073 mL	6.5365 mL
20 mM	0.0654 mL	0.3268 mL	0.6536 mL	3.2682 mL
50 mM	0.0261 mL	0.1307 mL	0.2615 mL	1.3073 mL
100 mM	0.0131 mL	0.0654 mL	0.1307 mL	0.6536 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc