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Dafsolimab (Synonyms: SPV-T3a)
Catalog No. T80597 Copy Product Info
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Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is utilized in research pertaining to graft-versus-host disease (GVHD) [1].
Dafsolimab
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Catalog No. T80597
Synonyms SPV-T3a
Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is utilized in research pertaining to graft-versus-host disease (GVHD) [1].
Dafsolimab
Cas No. 2367001-71-4
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Storage & Solubility Information
| Description | Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is utilized in research pertaining to graft-versus-host disease (GVHD) [1]. |
| In vitro | In the absence of PHA activation, SPV-T3a-dgA (1.8 μg/mL) resulted in a 2.0-2.7 fold reduction in viable cell count. After 48 hours of PHA activation, the cytotoxicity of SPV-T3a-DGA increased approximately threefold. |
| Synonyms | SPV-T3a |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | CD3 |
| Cas No. | 2367001-71-4 |
| Storage | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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