Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is utilized in research pertaining to graft-versus-host disease (GVHD) [1].
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Description | Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is utilized in research pertaining to graft-versus-host disease (GVHD) [1]. |
In vitro | In the absence of PHA activation, SPV-T3a-dgA (1.8 μg/mL) resulted in a 2.0-2.7 fold reduction in viable cell count. After 48 hours of PHA activation, the cytotoxicity of SPV-T3a-DGA increased approximately threefold. |
Synonyms | SPV-T3a |
Molecular Weight | N/A |
CAS No. | 2367001-71-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Dafsolimab 2367001-71-4 SPV-T3a inhibitor inhibit