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Maclurin

Name: Maclurin
Brand: TargetMol
SKU: T20578
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20578Cas No. 519-34-6

Alias NSC 83240, Morintannic acid, Fustic extract

Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of many diseases or MSCs transplantation.

Maclurin

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Purity: 99.71%

Catalog No. T20578Alias NSC 83240, Morintannic acid, Fustic extractCas No. 519-34-6

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$30	In Stock	In Stock
5 mg	$48	In Stock	In Stock
10 mg	$68	In Stock	In Stock
25 mg	$108	In Stock	In Stock
50 mg	$156	In Stock	In Stock
100 mg	$219	In Stock	In Stock
200 mg	$325	-	In Stock
1 mL x 10 mM (in DMSO)	$53	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.71%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of many diseases or MSCs transplantation.
In vitro	Maclurin effectively protects against mesenchymal stem cells (MSCs) oxidative damage induced by hydroxyl radical (OH) at 62.1-310.5 μM. Maclurin efficiently protects DNA from OH-induced damage at 114.6-382.2 μM, and scavenge OH, DPPH, ABTS(+), and bind Cu(2+) with IC50s of 122.87, 10.15, 0.97, and 133.95 μM[1].
Synonyms	NSC 83240, Morintannic acid, Fustic extract

Chemical Properties

Molecular Weight	262.21
Formula	C₁₃H₁₀O₆
Cas No.	519-34-6
Smiles	C(=O)(C1=C(O)C=C(O)C=C1O)C2=CC(O)=C(O)C=C2
Relative Density.	1.641 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (953.43 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.81 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8137 mL	19.0687 mL	38.1374 mL	190.6869 mL
5 mM	0.7627 mL	3.8137 mL	7.6275 mL	38.1374 mL
10 mM	0.3814 mL	1.9069 mL	3.8137 mL	19.0687 mL
20 mM	0.1907 mL	0.9534 mL	1.9069 mL	9.5343 mL
50 mM	0.0763 mL	0.3814 mL	0.7627 mL	3.8137 mL
100 mM	0.0381 mL	0.1907 mL	0.3814 mL	1.9069 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc