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Mogroside IIA1

Name: Mogroside IIA1
Brand: TargetMol
SKU: TN1934
Price: 251 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1934Cas No. 88901-44-4

Alias Mogroside II-A1

Mogroside IIA1 (Mogroside II-A1) is isolated from the fruits of Siraitia grosvenorii. Mogroside IIA1 is a a nonsugar sweetener and sweeter than sucrose. Mogroside IIA1 possesses antioxidant, antidiabetic and anticancer activities.

Mogroside IIA1

🥰Excellent

Purity: 99.60%

Catalog No. TN1934Alias Mogroside II-A1Cas No. 88901-44-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$43	-	In Stock
5 mg	$101	In Stock	In Stock
10 mg	$150	In Stock	In Stock
25 mg	$251	-	In Stock
50 mg	Preferential	-	In Stock
1 mL x 10 mM (in DMSO)	$162	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.60%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Mogroside IIA1 (Mogroside II-A1) is isolated from the fruits of Siraitia grosvenorii. Mogroside IIA1 is a a nonsugar sweetener and sweeter than sucrose. Mogroside IIA1 possesses antioxidant, antidiabetic and anticancer activities.
In vitro	Mogroside II-A1 exhibits inhibitory effects with IC50 values of 346-400 mol ratio/32 pmol TPA. Mogroside II-A1 showed weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor[1].
Synonyms	Mogroside II-A1

Chemical Properties

Molecular Weight	801.01
Formula	C₄₂H₇₂O₁₄
Cas No.	88901-44-4
Smiles	[H][C@@]1(CC[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(CC[C@H](O)C4(C)C)[C@]3(C)[C@H](O)C[C@]12C)[C@H](C)CC[C@@H](O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)C(C)(C)O
Relative Density.	1.33 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95 mg/mL (118.60 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (4.12 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2484 mL	6.2421 mL	12.4842 mL	62.4212 mL
5 mM	0.2497 mL	1.2484 mL	2.4968 mL	12.4842 mL
10 mM	0.1248 mL	0.6242 mL	1.2484 mL	6.2421 mL
20 mM	0.0624 mL	0.3121 mL	0.6242 mL	3.1211 mL
50 mM	0.0250 mL	0.1248 mL	0.2497 mL	1.2484 mL
100 mM	0.0125 mL	0.0624 mL	0.1248 mL	0.6242 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc