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Anti-CEACAM1 Antibody (7X389)
😃Good
Catalog No. TMAY-03781
Alias CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP
Anti-CEACAM1 Antibody (7X389) is a Mouse antibody targeting CEACAM1. Anti-CEACAM1 Antibody (7X389) can be used in ELISA.
Anti-CEACAM1 Antibody (7X389)
Anti-CEACAM1 Antibody (7X389)
😃Good
Catalog No. TMAY-03781Alias CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP
Anti-CEACAM1 Antibody (7X389) is a Mouse antibody targeting CEACAM1. Anti-CEACAM1 Antibody (7X389) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Rat |
| Alias | CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP |
| Ig Type | Mouse IgG1 |
| Clone | 7X389 |
| Reactivity | Rat |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CEACAM1 / CD66a (TMPY-03240; Met1-Ser422). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Rat CEACAM1 / CD66a protein (TMPY-03240) |
| Antigen Species | Rat |
| Biology Area | Cancer Drug Targets, ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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