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Anti-CEACAM1 Antibody (7X389) (Synonyms: CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molec...)

Name: Anti-CEACAM1 Antibody (7X389)
Brand: TargetMol
SKU: TMAY-03781
Rating: 4.5 (1 reviews)

Catalog No. TMAY-03781 Copy Product Info

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Anti-CEACAM1 Antibody (7X389) is a Mouse antibody targeting CEACAM1. Anti-CEACAM1 Antibody (7X389) can be used in ELISA.

Anti-CEACAM1 Antibody (7X389)

Copy Product Info

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Catalog No. TMAY-03781

Synonyms CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP

Anti-CEACAM1 Antibody (7X389) is a Mouse antibody targeting CEACAM1. Anti-CEACAM1 Antibody (7X389) can be used in ELISA.

Anti-CEACAM1 Antibody
(7X389)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$199	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-CEACAM1 Antibody (7X389) is a Mouse antibody targeting CEACAM1. Anti-CEACAM1 Antibody (7X389) can be used in ELISA.
Synonyms	CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP
Ig Type	Mouse IgG1
Clone	7X389
Reactivity	Rat
Specificity	Rat CEACAM-1/CD66a No cross-reactivity in ELISA with Human CEACAM1 Human CEACAM3 Human CEACAM5 Human CEACAM6 Human cell lysate (293 cell line)
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CEACAM1 / CD66a (TMPY-03240; Met1-Ser422). The IgG fraction of the cell culture supernatant was purified by Protein A affinity.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Rat CEACAM1 / CD66a protein (TMPY-03240)
Antigen Species	Rat
Biology Area	Cancer Drug Targets, ITIM/ITAM Immunoreceptors and Related Molecules

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

biliary glycoproteinBGP-1BGP 1

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