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IRAK inhibitor 2

Name: IRAK inhibitor 2
Brand: TargetMol
SKU: T7368
Price: 78 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7368Cas No. 928333-30-6

Alias IRAK-IN-2

IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.

IRAK inhibitor 2

🥰Excellent

Purity: 99.58%

Catalog No. T7368Alias IRAK-IN-2Cas No. 928333-30-6

IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$78	-	In Stock
5 mg	$189	-	In Stock
10 mg	$272	-	In Stock
25 mg	$479	-	In Stock
50 mg	$689	-	In Stock
100 mg	$987	-	In Stock
500 mg	$1,980	-	In Stock
1 mL x 10 mM (in DMSO)	$198	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.58%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.
Synonyms	IRAK-IN-2

Chemical Properties

Molecular Weight	306.32
Formula	C₁₇H₁₄N₄O₂
Cas No.	928333-30-6
Smiles	Oc1ccc(cc1)-c1cnc2ccc(NCc3ccco3)nn12
Relative Density.	1.38 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (97.94 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.53 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2646 mL	16.3228 mL	32.6456 mL	163.2280 mL
5 mM	0.6529 mL	3.2646 mL	6.5291 mL	32.6456 mL
10 mM	0.3265 mL	1.6323 mL	3.2646 mL	16.3228 mL
20 mM	0.1632 mL	0.8161 mL	1.6323 mL	8.1614 mL
50 mM	0.0653 mL	0.3265 mL	0.6529 mL	3.2646 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc