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Trigonelline chloride

Name: Trigonelline chloride
Brand: TargetMol
SKU: T2927
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T2927Cas No. 6138-41-6

Alias Trigonelline hydrochloride, Nicotinic acid N-methylbetaine Hydrochloride, Gynesine Hydrochloride, Coffearine Hydrochloride

Trigonelline chloride (Coffearine Hydrochloride), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.

Trigonelline chloride

🥰Excellent

Purity: 99.93%

Catalog No. T2927Alias Trigonelline hydrochloride, Nicotinic acid N-methylbetaine Hydrochloride, Gynesine Hydrochloride, Coffearine HydrochlorideCas No. 6138-41-6

Trigonelline chloride (Coffearine Hydrochloride), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.

Pack Size	Price	Availability
50 mg	$37	In Stock
100 mg	$50	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Batch Information

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Purity:99.93%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Trigonelline chloride (Coffearine Hydrochloride), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
Synonyms	Trigonelline hydrochloride, Nicotinic acid N-methylbetaine Hydrochloride, Gynesine Hydrochloride, Coffearine Hydrochloride

Chemical Properties

Molecular Weight	173.6
Formula	C₇H₈ClNO₂
Cas No.	6138-41-6
Smiles	C[n+]1cccc(c1)C(=O)O.[Cl-]
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 4 mg/mL (23.04 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (5.76 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.7604 mL	28.8018 mL	57.6037 mL	288.0184 mL
5 mM	1.1521 mL	5.7604 mL	11.5207 mL	57.6037 mL
10 mM	0.5760 mL	2.8802 mL	5.7604 mL	28.8018 mL
20 mM	0.2880 mL	1.4401 mL	2.8802 mL	14.4009 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc