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JGB-1-155

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Catalog No. T86767Cas No. 3011930-28-9
Alias JGB1-155

JGB-1-155 is a positive allosteric modulator of nicotinamide phosphoribosyltransferase that enhances NAMPT enzymatic activity, elevates intracellular NAD⁺ levels in human monocytes, counteracts oxidative stress, and attenuates TNFα-induced reactive oxygen species production, supporting its application in studies of redox balance and inflammatory signaling.

JGB-1-155

JGB-1-155

😃Good
Catalog No. T86767Alias JGB1-155Cas No. 3011930-28-9
JGB-1-155 is a positive allosteric modulator of nicotinamide phosphoribosyltransferase that enhances NAMPT enzymatic activity, elevates intracellular NAD⁺ levels in human monocytes, counteracts oxidative stress, and attenuates TNFα-induced reactive oxygen species production, supporting its application in studies of redox balance and inflammatory signaling.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5208-10 weeks8-10 weeks
50 mg$1,9808-10 weeks8-10 weeks
100 mg$2,5008-10 weeks8-10 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
JGB-1-155 is a positive allosteric modulator of nicotinamide phosphoribosyltransferase that enhances NAMPT enzymatic activity, elevates intracellular NAD⁺ levels in human monocytes, counteracts oxidative stress, and attenuates TNFα-induced reactive oxygen species production, supporting its application in studies of redox balance and inflammatory signaling.
In vitro
In biochemical assays, JGB-1-155 significantly activated the NAMPT enzyme with an EC50 of 0.026 μM and protected the cells from oxidative stress-induced death [1].
SynonymsJGB1-155
Chemical Properties
Molecular Weight426.59
FormulaC26H38N2O3
Cas No.3011930-28-9
SmilesO=C(C=1OC=CC1)N(CC2=CC=C(C=C2)N(C)C)CCC3(CCOC(C)(C)C3)C(C)C
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice.

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Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

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