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Anti-IFIH1 Antibody (8B90)
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Catalog No. TMAH-00592
Anti-IFIH1 Antibody (8B90) is an antibody targeting IFIH1. Anti-IFIH1 Antibody (8B90) can be used in ELISA, WB.
Anti-IFIH1 Antibody (8B90)
Anti-IFIH1 Antibody (8B90)
😃Good
Catalog No. TMAH-00592
Anti-IFIH1 Antibody (8B90) is an antibody targeting IFIH1. Anti-IFIH1 Antibody (8B90) can be used in ELISA, WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $208 | 7-10 days | |
| 100 μL | $349 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IFIH1 Antibody (8B90) is an antibody targeting IFIH1. Anti-IFIH1 Antibody (8B90) can be used in ELISA, WB. |
| Ig Type | Rabbit IgG |
| Clone | 8B90 |
| Reactivity | Human, Mouse |
| Verified Activity | Western Blot -Positive WB detected in: THP-1 whole cell lysate, Mouse lung tissue -All lanes: MDA5 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 117, 26 kDa -Observed band size: 117 kDa |
| Application | ELISA, WB |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus. Mitochondrion. Note=Upon viral RNA stimulation and ISGylation, translocates from cytosol to mitochondrion. May be found in the nucleus, during apoptosis. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include mRNA lacking 2'-O-methylation at their 5' cap and long-dsRNA (>1 kb in length). Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases: TBK1 and IKBKE which phosphorylate interferon regulatory factors: IRF3 and IRF7 which... |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human MDA5 |
| Antigen Species | Human |
| Gene ID | 64135 |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Immunology, Microbiology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
RNA helicase-DEAD box protein 116RLR-2RLR2RIG-I-like receptor 2 (RLR-2)RH116RH 116Murabutide down-regulated proteinMelanoma differentiation-associated protein 5 (MDA-5)MDA-5MDA5MDA 5Interferon-induced with helicase C domain protein 1Interferon-induced helicase C domain-containing protein 1IFIH1IFIH 1Helicase with 2 CARD domains (Helicard)HelicardClinically amyopathic dermatomyositis autoantigen 140 kDa (CADM-140 autoantigen)CADM-140 autoantigenCADM140 autoantigen
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