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Anti-ICAM-1/CD54 Antibody (7D308) (Alias: P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2)
Catalog No. TMAY-03293 Copy Product Info
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Anti-ICAM-1/CD54 Antibody (7D308) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (7D308) can be used in FCM,ICC/IF.
Anti-ICAM-1/CD54 Antibody (7D308)
Copy Product Info🥰Excellent
Catalog No. TMAY-03293
Alias P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2
Anti-ICAM-1/CD54 Antibody (7D308) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (7D308) can be used in FCM,ICC/IF.
Anti-ICAM-1/CD54 Antibody
(7D308)
(7D308)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-ICAM-1/CD54 Antibody (7D308) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (7D308) can be used in FCM,ICC/IF. |
| Synonyms | P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2 |
| Ig Type | Rabbit IgG |
| Clone | 7D308 |
| Reactivity | Mouse |
| Specificity | Mouse ICAM-1/CD54 |
| Verified Activity | 1. Flow cytometric analysis of Mouse ICAM1(CD54) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse ICAM1(CD54), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. 2. Immunofluorescence staining of Mouse ICAM1 in Raw264.7 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-mouse ICAM1 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm and Cell membrane. |
| Application | |
| Recommended Dose | ICC-IF: 1:20-1:100; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ICAM-1 / CD54 (rM ICAM-1 / CD54; TMPY-01349; NP_034623.1; Met1-Asn485). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM-1 is a ligand for LFA-1(integrin). When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM-1 possesses binding sites for some immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM-1 also becomes known for its affinity for Plasmodium falciparum-infected erythrocytes (PFIE), providing more of a role in infectious disease. Previous studies have shown that ICAM-1 is involved in inflammatory reactions and that a defect in ICAM-1 gene inhibits allergic contact hypersensitivity. |
| Conjucates | Unconjugated |
| Others Formats | FITC/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Protein: Mouse ICAM-1 / CD54 Protein (TMPY-01349) |
| Antigen Species | Mouse |
| Biology Area | Neuroinflammation |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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