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N-Nitroso Sarcosine

Catalog No. T36414 CAS 13256-22-9

N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine that has been found in cured meat products.1,2

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N-Nitroso Sarcosine, CAS 13256-22-9

Pack Size	Availability	Price/USD	Quantity
10 mg	35 days	$ 110.00
100 mg	35 days	$ 643.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine that has been found in cured meat products.1,2
In vivo	In vivo, N-nitroso sarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice.2

Molecular Weight	118.0913
Formula	C3H6N2O3
CAS No.	13256-22-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL

DMF: 15 mg/mL

Ethanol: 30 mg/mL

PBS (pH 7.2): 5 mg/mL

References and Literature

1. Janzowski, C., Eisenbrand, G., and Preussmann, R.Occurrence of N-nitrosamino acids in cured meat products and their efffect on formation of N-nitrosamines during heatingFood Cosmet. Toxicol.16(4)343-348(1978) 2. Wogan, G.N., Paglialunga, S., Archer, M.C., et al.Carcinogenicity of nitrosation products of ephedrine, sarcosine, folic acid, and creatinineCancer Res.35(8)1981-1984(1975)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

N-Nitroso Sarcosine 13256-22-9 N Nitroso Sarcosine NNitroso Sarcosine inhibitor inhibit

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