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NoxA1ds TFA

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Catalog No. T75949

NoxA1ds TFA is a potent and selective inhibitor of NADPH oxidase 1 (NOX1) with an inhibition concentration (IC50) of 20 nM, showing selectivity over NOX2, NOX4, NOX5, and xanthine oxidase. It effectively inhibits NOX1-derived O2- production in HT-29 human colon cancer cells and attenuates VEGF-induced migration of human pulmonary artery endothelial cells under hypoxic conditions in vitro.

NoxA1ds TFA
Other Forms of NoxA1ds TFA:

NoxA1ds TFA

😃Good
Catalog No. T75949
NoxA1ds TFA is a potent and selective inhibitor of NADPH oxidase 1 (NOX1) with an inhibition concentration (IC50) of 20 nM, showing selectivity over NOX2, NOX4, NOX5, and xanthine oxidase. It effectively inhibits NOX1-derived O2- production in HT-29 human colon cancer cells and attenuates VEGF-induced migration of human pulmonary artery endothelial cells under hypoxic conditions in vitro.
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Product Introduction

Bioactivity
Description
NoxA1ds TFA is a potent and selective inhibitor of NADPH oxidase 1 (NOX1) with an inhibition concentration (IC50) of 20 nM, showing selectivity over NOX2, NOX4, NOX5, and xanthine oxidase. It effectively inhibits NOX1-derived O2- production in HT-29 human colon cancer cells and attenuates VEGF-induced migration of human pulmonary artery endothelial cells under hypoxic conditions in vitro.
Chemical Properties
Molecular Weight1239.35
FormulaC52H89F3N14O17
Sequence ShortEPVDALGKAKV-NH2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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