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ABBV-303
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Catalog No. T9901A-054 Copy Product Info
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ABBV-303 is a multispecific NK cell antibody utilizing TriNKET technology to target c-Met for NK cell redirection therapy. It comprises three functional components: a single-chain variable fragment (scFV) targeting c-Met, a Fab arm engaging NKG2D, and an Fc fragment directed at NK cell CD16a [1].
ABBV-303
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | ABBV-303 is a multispecific NK cell antibody utilizing TriNKET technology to target c-Met for NK cell redirection therapy. It comprises three functional components: a single-chain variable fragment (scFV) targeting c-Met, a Fab arm engaging NKG2D, and an Fc fragment directed at NK cell CD16a [1]. |
| In vitro | ABBV-303 consists of three functional arms: (1) the single-chain variable fragment (scFV) is derived from ABT-700 and is a common fragment in the c-Met targeting antibody-drug conjugates (ADCs) ABBV-400 and Teliso-V; (2) the Fab arm targets NKG2D, facilitating binding with cells expressing NKG2D, such as NK cells and activated CD8+ T cells; (3) the conventional Fc fragment is an IgG1 Fc heterodimer that targets CD16a on NK cells and connects the other two functional arms of ABBV-303. |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: ABBV-303 in vitro
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