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D-Alanine

🥰Excellent
Catalog No. T4811Cas No. 338-69-2
Alias D-α-Alanine, Ba 2776, (R)-Alanine, (R)-2-Aminopropionic acid

Alanine is a nonessential amino acid made in the body from the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine. D-Alanine ((R)-Alanine) is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

D-Alanine
Other Forms of D-Alanine:

D-Alanine

🥰Excellent
Purity: 99.81%
Catalog No. T4811Alias D-α-Alanine, Ba 2776, (R)-Alanine, (R)-2-Aminopropionic acidCas No. 338-69-2
Alanine is a nonessential amino acid made in the body from the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine. D-Alanine ((R)-Alanine) is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
Pack SizePriceAvailabilityQuantity
500 mg$29In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:99.81%
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COA LCMS HPLC HNMR

Product Introduction

Bioactivity
Description
Alanine is a nonessential amino acid made in the body from the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine. D-Alanine ((R)-Alanine) is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
Targets&IC50
GlyR:9 mM (EC50)
SynonymsD-α-Alanine, Ba 2776, (R)-Alanine, (R)-2-Aminopropionic acid
Chemical Properties
Molecular Weight89.09
FormulaC3H7NO2
Cas No.338-69-2
SmilesC[C@@H](N)C(O)=O
Relative Density.1.161g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Slightly soluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

weakPMBAinhibitoryInhibitorinhibitGlyRGlycine receptorglycineEndogenousMetaboliteEndogenous MetaboliteD-alpha-AlanineD-AlanineDAlanineD-a-AlanineD AlanineChloridechannelChloride channelBa-2776Ba2776Alanine2-Aminopropionic acid
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