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IDO-IN-6

Name: IDO-IN-6
Brand: TargetMol
SKU: T11620
Rating: 4.5 (1 reviews)

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Catalog No. T11620Cas No. 1402837-76-6

Alias NLG-1486

IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor.

IDO-IN-6

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Catalog No. T11620Alias NLG-1486Cas No. 1402837-76-6

IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor.

Pack Size	Price	Availability	Quantity
10 mg	$1,190	6-8 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor.
Targets&IC50	IDO:1 μM
In vitro	IDO-IN-6 ?is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of <1 μM (this is the concentration of IDO-IN-6 at which inhibits 50% of enzymatic activity using recombinant human IDO).
Synonyms	NLG-1486

Chemical Properties

Molecular Weight	316.37
Formula	C₁₈H₂₁FN₂O₂
Cas No.	1402837-76-6
Relative Density.	1.42 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (158.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1609 mL	15.8043 mL	31.6086 mL	158.0428 mL
5 mM	0.6322 mL	3.1609 mL	6.3217 mL	31.6086 mL
10 mM	0.3161 mL	1.5804 mL	3.1609 mL	15.8043 mL
20 mM	0.1580 mL	0.7902 mL	1.5804 mL	7.9021 mL
50 mM	0.0632 mL	0.3161 mL	0.6322 mL	3.1609 mL
100 mM	0.0316 mL	0.1580 mL	0.3161 mL	1.5804 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc