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Neoline

🥰Excellent
Catalog No. T4S0537Cas No. 466-26-2
Alias Bullatine B

Neoline is an active ingredient of A. venetum root (PA) that ameliorates oxaliplatin-induced peripheral neuropathy in mice.Neoline inhibits Nav1.7 voltage-gated sodium channel currents (VGSC). It can be used as a labeling compound to determine the quality of PA products used in the study of neuropathic pain.

Neoline

Neoline

🥰Excellent
Purity: 99.97%
Catalog No. T4S0537Alias Bullatine BCas No. 466-26-2
Neoline is an active ingredient of A. venetum root (PA) that ameliorates oxaliplatin-induced peripheral neuropathy in mice.Neoline inhibits Nav1.7 voltage-gated sodium channel currents (VGSC). It can be used as a labeling compound to determine the quality of PA products used in the study of neuropathic pain.
Pack SizePriceAvailabilityQuantity
5 mg$38In Stock
10 mg$68In Stock
25 mgPreferentialIn Stock
50 mgPreferentialIn Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:99.97%
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Product Introduction

Bioactivity
Description
Neoline is an active ingredient of A. venetum root (PA) that ameliorates oxaliplatin-induced peripheral neuropathy in mice.Neoline inhibits Nav1.7 voltage-gated sodium channel currents (VGSC). It can be used as a labeling compound to determine the quality of PA products used in the study of neuropathic pain.
SynonymsBullatine B
Chemical Properties
Molecular Weight437.57
FormulaC24H39NO6
Cas No.466-26-2
Smiles[H][C@]12C[C@]3([H])[C@]([H])([C@H]1O)[C@](O)(C[C@@H]2OC)[C@@]1([H])[C@H](OC)[C@@]2([H])C33[C@@H](O)CC[C@@]2(COC)CN(CC)[C@]13[H]
Relative Density.1.31 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
DMSO: 200 mg/mL (457.07 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2853 mL11.4267 mL22.8535 mL114.2674 mL
5 mM0.4571 mL2.2853 mL4.5707 mL22.8535 mL
10 mM0.2285 mL1.1427 mL2.2853 mL11.4267 mL
20 mM0.1143 mL0.5713 mL1.1427 mL5.7134 mL
50 mM0.0457 mL0.2285 mL0.4571 mL2.2853 mL
100 mM0.0229 mL0.1143 mL0.2285 mL1.1427 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

SodiumChannelSodium Channelperipheralpainoxaliplatin-inducedneuropathyneuropathicNeolineNav1.7 channelInhibitorinhibit
Related Tags: buy Neoline | purchase Neoline | Neoline cost | order Neoline | Neoline chemical structure | Neoline formula | Neoline molecular weight
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