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Histatin 8 TFA

Name: Histatin 8 TFA
Brand: TargetMol
SKU: T83689
Rating: 4.5 (1 reviews)

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Catalog No. T83689

Alias Hst-8

Histatin 8, a salivary antimicrobial peptide derived from proteolytic fragments of histatin 3 and histatin 5, exhibits activity against A. baumannii strains, both colistin-susceptible and -resistant, at a concentration of 32 µg/ml. Additionally, it is effective against C. albicans and C. tropicalis, with minimum inhibitory concentrations (MICs) of 1 and 5 mg/ml, respectively.

Histatin 8 TFA

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Catalog No. T83689Alias Hst-8

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$55	Inquiry	Inquiry
5 mg	$244	Inquiry	Inquiry
10 mg	$428	Inquiry	Inquiry
25 mg	$939	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Histatin 8, a salivary antimicrobial peptide derived from proteolytic fragments of histatin 3 and histatin 5, exhibits activity against A. baumannii strains, both colistin-susceptible and -resistant, at a concentration of 32 µg/ml. Additionally, it is effective against C. albicans and C. tropicalis, with minimum inhibitory concentrations (MICs) of 1 and 5 mg/ml, respectively.
Synonyms	Hst-8

Chemical Properties

Molecular Weight	1562.69
Formula	C₇₀H₉₉N₂₅O₁₇.XCF₃COOH
Smiles	OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CC2=CN=CN2)NC([C@H](CO)NC([C@H](CC3=CN=CN3)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H](NC([C@@H](N)CCCCN)=O)CC4=CC=CC=C4)=O)CC5=CN=CN5)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Sequence	Lys-Phe-Glu-Lys-Ser-Arg-Gly-Tyr
Sequence Short	KFXEKXXSXRGY

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (6.4 mM), Sonication is recommended.

PBS pH 7.2: 10 mg/mL (6.4 mM), Sonication is recommended.

Ethanol: Slightly soluble

Chloroform: Slightly soluble

DMF: 10 mg/mL (6.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO/PBS pH 7.2/DMF

	1mg	5mg	10mg	50mg
1 mM	0.6399 mL	3.1996 mL	6.3992 mL	31.9961 mL
5 mM	0.1280 mL	0.6399 mL	1.2798 mL	6.3992 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc