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Histatin 8 TFA

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Catalog No. T83689
Alias Hst-8

Histatin 8, a salivary antimicrobial peptide derived from proteolytic fragments of histatin 3 and histatin 5, exhibits activity against A. baumannii strains, both colistin-susceptible and -resistant, at a concentration of 32 µg/ml. Additionally, it is effective against C. albicans and C. tropicalis, with minimum inhibitory concentrations (MICs) of 1 and 5 mg/ml, respectively.

Histatin 8 TFA

Histatin 8 TFA

😃Good
Catalog No. T83689Alias Hst-8
Histatin 8, a salivary antimicrobial peptide derived from proteolytic fragments of histatin 3 and histatin 5, exhibits activity against A. baumannii strains, both colistin-susceptible and -resistant, at a concentration of 32 µg/ml. Additionally, it is effective against C. albicans and C. tropicalis, with minimum inhibitory concentrations (MICs) of 1 and 5 mg/ml, respectively.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$55InquiryInquiry
5 mg$244InquiryInquiry
10 mg$428InquiryInquiry
25 mg$939InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Histatin 8, a salivary antimicrobial peptide derived from proteolytic fragments of histatin 3 and histatin 5, exhibits activity against A. baumannii strains, both colistin-susceptible and -resistant, at a concentration of 32 µg/ml. Additionally, it is effective against C. albicans and C. tropicalis, with minimum inhibitory concentrations (MICs) of 1 and 5 mg/ml, respectively.
SynonymsHst-8
Chemical Properties
Molecular Weight1562.69
FormulaC70H99N25O17.XCF3COOH
SmilesOC(C=C1)=CC=C1C[C@@H](C(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CC2=CN=CN2)NC([C@H](CO)NC([C@H](CC3=CN=CN3)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H](NC([C@@H](N)CCCCN)=O)CC4=CC=CC=C4)=O)CC5=CN=CN5)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Sequence ShortKFXEKXXSXRGY
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (6.4 mM), Sonication is recommended.
PBS pH 7.2: 10 mg/mL (6.4 mM), Sonication is recommended.
Ethanol: Slightly soluble
Chloroform: Slightly soluble
DMF: 10 mg/mL (6.4 mM), Sonication is recommended.
Solution Preparation Table
DMSO/PBS pH 7.2/DMF
1mg5mg10mg50mg
1 mM0.6399 mL3.1996 mL6.3992 mL31.9961 mL
5 mM0.1280 mL0.6399 mL1.2798 mL6.3992 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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