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Benzoic acid

Name: Benzoic acid
Brand: TargetMol
SKU: T0833
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0833Cas No. 65-85-0

Alias FEMA 2131, Dracylic acid

Benzoic acid (Dracylic acid) is a fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.

Benzoic acid

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Purity: 98.09%

Catalog No. T0833Alias FEMA 2131, Dracylic acidCas No. 65-85-0

Benzoic acid (Dracylic acid) is a fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.09%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS HPLC

Product Introduction

Bioactivity

Description	Benzoic acid (Dracylic acid) is a fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
In vivo	Under acidic growth conditions, Benzoic acid readily enters cells where its intracellular ionization significantly reduces both the intracellular pH and the levels of adenosine triphosphatase (ATPase). Benzoic acid is susceptible to oxidation by hydroxyl radicals produced by stimulated neutrophils. The average absorption of Benzoic acid through human skin shows no difference from that in rat studies, being minimally affected by skin thickness. The maximum rate of Benzoic acid transport across human skin cell membranes is 16.54 μg/cm2 per hour, with an actual dose of 70.6% in the receptor fluid after 24 hours.
Synonyms	FEMA 2131, Dracylic acid

Chemical Properties

Molecular Weight	122.12
Formula	C₇H₆O₂
Cas No.	65-85-0
Smiles	O=C(O)C=1C=CC=CC1
Relative Density.	1.321 g/cm3. Temperature:20 °C.;1.082 g/cm3. Temperature:122.375 °C.;1.029 g/cm3. Temperature:180 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 24 mg/mL (196.53 mM), Sonication is recommended.

DMSO: 60 mg/mL (491.32 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (16.38 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	8.1887 mL	40.9433 mL	81.8867 mL	409.4333 mL
5 mM	1.6377 mL	8.1887 mL	16.3773 mL	81.8867 mL
10 mM	0.8189 mL	4.0943 mL	8.1887 mL	40.9433 mL
20 mM	0.4094 mL	2.0472 mL	4.0943 mL	20.4717 mL
50 mM	0.1638 mL	0.8189 mL	1.6377 mL	8.1887 mL
100 mM	0.0819 mL	0.4094 mL	0.8189 mL	4.0943 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc