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Futuximab

Catalog No. T77015 Copy Product Info
Purity: 95%
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Futuximab is a chimeric monoclonal antibody targeting EGFR, commonly used in combination with zatuximab to form Sym004. Sym004 targets non-overlapping epitopes on EGFR, exhibiting antitumour activity.

Futuximab

Copy Product Info
🥰Excellent
Catalog No. T77015

Futuximab is a chimeric monoclonal antibody targeting EGFR, commonly used in combination with zatuximab to form Sym004. Sym004 targets non-overlapping epitopes on EGFR, exhibiting antitumour activity.

Futuximab
Cas No. 1310460-85-5
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$745-In Stock
10 mg$1,180-In Stock
25 mg$1,770-In Stock
50 mg$2,380-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97.5% (SDS-PAGE); 96.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Futuximab is a chimeric monoclonal antibody targeting EGFR, commonly used in combination with zatuximab to form Sym004. Sym004 targets non-overlapping epitopes on EGFR, exhibiting antitumour activity.
In vitro
In NR6M cells, Futuximab (20 µg/mL, 24-48 hours) induced EGFRvIII internalization and caused a slight decrease in EGFRvIII levels [1].
In vivo
In the EGFRwt-expressing parazacco spilurus subsp. spilurus xenograft model, Futuximab (50 mg/kg, intraperitoneal injection, twice weekly for 5 consecutive weeks) demonstrated significant antitumor activity [1].
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetERBB1/EGFR/HER1
Chemical Properties
Molecular Weight146.28 kDa
Cas No.1310460-85-5
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature | Store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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