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C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord, and sciatic nerve at one, three, and six months of age.4
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $292 | Backorder | |
5 mg | $810 | Backorder |
Description | C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord, and sciatic nerve at one, three, and six months of age.4 |
Alias | C24 dihydro 1-Deoxyceramide (m18:0/24:0) |
Molecular Weight | 636.147 |
Formula | C42H85NO2 |
Cas No. | 1645269-63-1 |
Relative Density. | 0.876 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMF: 20 mg/mL (31.44 mM), Sonication is recommended. Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/mL (0.79 mM), Sonication is recommended. Ethanol: 30 mg/mL (47.16 mM), Sonication is recommended. DMSO: 20 mg/mL (31.44 mM), Sonication is recommended. |
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