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Isobavachin

Name: Isobavachin
Brand: TargetMol
SKU: T3931
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T3931 Copy Product Info

Purity: 99.97%

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Isobavachin can facilitate mouse ES cells differentiating into neuronal cells.

Isobavachin

Copy Product Info

😃Good

Catalog No. T3931

Isobavachin can facilitate mouse ES cells differentiating into neuronal cells.

Cas No. 31524-62-6

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Pack Size	Price	USA Stock	Global Stock
1 mg	$34	In Stock	In Stock
5 mg	$64	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$168	In Stock	In Stock
50 mg	$249	In Stock	In Stock
100 mg	$397	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock	In Stock

In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.97%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Isobavachin AI Summary

Isobavachin exhibits significant bioactivities including cytotoxicity against human Raji cells with an activity of 70.0% at a 1000 molar ratio, and variable inhibition (0.0% to 88.6%) of TPA-induced EBV-early antigen activation in these cells. It also shows a scavenging activity against nitric oxide (NO) generation in human Chang liver cells with a ratio of 1.2. Moreover, compound 461850 demonstrates notable anti-inflammatory properties by inhibiting nitric oxide production in mouse RAW264.7 cells stimulated with LPS, with an IC50 of 47000.0 nM after 24 hours, as measured by the Griess method..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Isobavachin can facilitate mouse ES cells differentiating into neuronal cells.

Chemical Properties

Molecular Weight	324.37
Formula	C₂₀H₂₀O₄
Cas No.	31524-62-6
Smiles	CC(C)=CCc1c(O)ccc2C(=O)C[C@H](Oc12)c1ccc(O)cc1
Relative Density.	1.244 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 59 mg/mL (181.89 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.17 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0829 mL	15.4145 mL	30.8290 mL	154.1450 mL
5 mM	0.6166 mL	3.0829 mL	6.1658 mL	30.8290 mL
10 mM	0.3083 mL	1.5414 mL	3.0829 mL	15.4145 mL
20 mM	0.1541 mL	0.7707 mL	1.5414 mL	7.7072 mL
50 mM	0.0617 mL	0.3083 mL	0.6166 mL	3.0829 mL
100 mM	0.0308 mL	0.1541 mL	0.3083 mL	1.5414 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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Dilution Calculator
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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc