Dendrotoxin-I

Name: Dendrotoxin-I
Brand: TargetMol
SKU: T80064
Rating: 4.5 (1 reviews)

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Catalog No. T80064Cas No. 107950-33-4

Alias DTX-I

Dendrotoxin-I, a neurotoxin from Dendroaspis snake venom, potently blocks K⁺ channels, specifically targeting voltage-gated potassium channel subunits KV1.1 and KV1.2 [1] [2] [3].

Dendrotoxin-I

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Catalog No. T80064Alias DTX-ICas No. 107950-33-4

Dendrotoxin-I, a neurotoxin from Dendroaspis snake venom, potently blocks K⁺ channels, specifically targeting voltage-gated potassium channel subunits KV1.1 and KV1.2 [1] [2] [3].

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Product Introduction

Bioactivity

Description	Dendrotoxin-I, a neurotoxin from Dendroaspis snake venom, potently blocks K⁺ channels, specifically targeting voltage-gated potassium channel subunits KV1.1 and KV1.2 [1] [2] [3].
Targets&IC50	Kv1.6:0.13-50 nM, Kv1.2:0.13-50 nM, Kv1.1:0.13-50 nM
In vivo	Dendrotoxin-I (5 mg/kg; IV) significantly inhibits tumor growth when combined with hyperthermia [3].
Alias	DTX-I

Chemical Properties

Molecular Weight	7149.24
Formula	C₃₁₂H₄₉₁N₉₉O₈₃S₆
Cas No.	107950-33-4

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

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