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(-)-Sesamin

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Catalog No. TN6905Cas No. 13079-95-3

(-)-Sesamin is a natural product with neuroprotective effects. It protects against 6-OHDA-induced neurotoxicity by activating ERK1/2-BadSer112 and inhibiting ERK-p38MAPK-JNK1/2-caspase-3 pathways, making it useful for Parkinson's disease research.

(-)-Sesamin
Other Forms of (-)-Sesamin:

(-)-Sesamin

😃Good
Purity: 99.36%
Catalog No. TN6905Cas No. 13079-95-3
(-)-Sesamin is a natural product with neuroprotective effects. It protects against 6-OHDA-induced neurotoxicity by activating ERK1/2-BadSer112 and inhibiting ERK-p38MAPK-JNK1/2-caspase-3 pathways, making it useful for Parkinson's disease research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$40-In Stock
25 mg$63-In Stock
50 mg$92-In Stock
100 mg$133-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.36%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
(-)-Sesamin is a natural product with neuroprotective effects. It protects against 6-OHDA-induced neurotoxicity by activating ERK1/2-BadSer112 and inhibiting ERK-p38MAPK-JNK1/2-caspase-3 pathways, making it useful for Parkinson's disease research.
Chemical Properties
Molecular Weight354.35
FormulaC20H18O6
Cas No.13079-95-3
Smiles[C@@]12([C@]([C@@H](OC1)C=3C=C4C(=CC3)OCO4)(CO[C@H]2C=5C=C6C(=CC5)OCO6)[H])[H]
Relative Density.1.385 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (225.77 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8221 mL14.1103 mL28.2207 mL141.1034 mL
5 mM0.5644 mL2.8221 mL5.6441 mL28.2207 mL
10 mM0.2822 mL1.4110 mL2.8221 mL14.1103 mL
20 mM0.1411 mL0.7055 mL1.4110 mL7.0552 mL
50 mM0.0564 mL0.2822 mL0.5644 mL2.8221 mL
100 mM0.0282 mL0.1411 mL0.2822 mL1.4110 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Sesamin()Sesamin( ) Sesamin
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