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Synonyms: Solute carrier family 16 member 1, Monocarboxylate transporter 1, MCT1, MCT 1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-SLC16A1 Antibody (8U24) is an antibody targeting SLC16A1. Anti-SLC16A1 Antibody (8U24) can be used in ELISA,IHC,WB. |
| Synonyms | Solute carrier family 16 member 1, Monocarboxylate transporter 1, MCT1, MCT 1 |
| Ig Type | Rabbit IgG |
| Clone | 8U24 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Monocarboxylic acid transporter 1 |
| Antigen Species | Human |
| Gene Name | SLC16A1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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