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Anti-ST2/IL-1 RL1 Antibody (6D935)

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Catalog No. TMAY-00264
Alias interleukin 1 receptor-like 1

Anti-ST2/IL-1 RL1 Antibody (6D935) is a Mouse antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (6D935) can be used in ELISA(Cap).

Anti-ST2/IL-1 RL1 Antibody (6D935)

Anti-ST2/IL-1 RL1 Antibody (6D935)

😃Good
Catalog No. TMAY-00264Alias interleukin 1 receptor-like 1
Anti-ST2/IL-1 RL1 Antibody (6D935) is a Mouse antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (6D935) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-ST2/IL-1 RL1 Antibody (6D935) is a Mouse antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (6D935) can be used in ELISA(Cap).
Aliasinterleukin 1 receptor-like 1
Ig Type
Monoclonal Mouse IgG1
Clone
6D935
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1RL1 / IL‑1 R4 (rh IL1RL1 / IL‑1 R4; TMPY-01359; NP_003847.2; Met1-Phe328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
Research BackgroundIL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human IL1RL1 / IL‑1 R4 Protein (TMPY-01359)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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