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Yadanziolide A

🥰Excellent
Catalog No. TN1130Cas No. 95258-14-3

Yadanziolide A is a natural product isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.

Yadanziolide A

Yadanziolide A

🥰Excellent
Purity: 99.54%
Catalog No. TN1130Cas No. 95258-14-3
Yadanziolide A is a natural product isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.
Pack SizePriceAvailabilityQuantity
1 mg$46In Stock
5 mg$98In Stock
10 mg$150In Stock
25 mg$249In Stock
50 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$120In Stock
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Purity:99.54%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Yadanziolide A is a natural product isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.
Targets&IC50
Tobacco mosaic virus:5.5 μM (IC50)
In vitro
The antitobacco mosaic virus (TMV) activity of these quassinoids was screened by the conventional half-leaf and leaf-disk method along with Western blot analysis[1]
Chemical Properties
Molecular Weight426.41
FormulaC20H26O10
Cas No.95258-14-3
Smiles[H][C@@]12C[C@@]3([H])C(C)=CC(=O)[C@@H](O)[C@]3(C)[C@@]3([H])[C@@H](O)[C@H](O)[C@@]4(CO)OC[C@@]13[C@@]4(O)[C@@H](O)C(=O)O2
Relative Density.1.68 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (234.52 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3452 mL11.7258 mL23.4516 mL117.2580 mL
5 mM0.4690 mL2.3452 mL4.6903 mL23.4516 mL
10 mM0.2345 mL1.1726 mL2.3452 mL11.7258 mL
20 mM0.1173 mL0.5863 mL1.1726 mL5.8629 mL
50 mM0.0469 mL0.2345 mL0.4690 mL2.3452 mL
100 mM0.0235 mL0.1173 mL0.2345 mL1.1726 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Yadanziolide AInhibitorinhibitantiviralAntifection
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