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Bimekizumab

(Synonyms: THPTA) Copy Product Info
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Synonyms: THPTA

Catalog No. T76798 Copy Product Info
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Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, capable of reducing IL17A/IL17F levels and blocking inflammation-driven osteoblast differentiation. It is applicable for investigating psoriasis and arthritis.
Bimekizumab
Cas No. 1418205-77-2
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$373-In Stock
5 mg$788-In Stock
10 mg$1,230-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>95.0% (SDS-PAGE)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, capable of reducing IL17A/IL17F levels and blocking inflammation-driven osteoblast differentiation. It is applicable for investigating psoriasis and arthritis.
In vitro
Methods: Bimekizumab (10 μg/mL, 1 hour) was used to treat human periosteum-derived cells (hPDCs), and the expression of osteogenesis-related genes was analyzed by real-time quantitative PCR.
Results: Bimekizumab effectively suppressed the expression of osteogenic genes through dual neutralization of IL-17A and IL-17F.[1]
SynonymsTHPTA
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-17a & IL-17f
Chemical Properties
Molecular Weight147.24 kDa
Cas No.1418205-77-2
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature,Keep away from direct sunlight Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Bimekizumab chemical structure | Bimekizumab in vitro | Bimekizumab molecular weight