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diABZI STING agonist-1

Name: diABZI STING agonist-1
Brand: TargetMol
SKU: T73746
Price: 148 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T73746Cas No. 2138299-33-7

diABZI STING agonist-1 is a selective and potent interferon gene-stimulating receptor (STING) agonist with potential antitumor and anti-inflammatory activity for the study of cancer.

diABZI STING agonist-1

🥰Excellent

Purity: 97.50%

Catalog No. T73746Cas No. 2138299-33-7

diABZI STING agonist-1 is a selective and potent interferon gene-stimulating receptor (STING) agonist with potential antitumor and anti-inflammatory activity for the study of cancer.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$148	In Stock	In Stock
5 mg	$372	In Stock	In Stock
10 mg	$533	In Stock	In Stock
25 mg	$786	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$578	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:97.50%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	diABZI STING agonist-1 is a selective and potent interferon gene-stimulating receptor (STING) agonist with potential antitumor and anti-inflammatory activity for the study of cancer.
In vivo	In Wild and Sting −/− C57Blk6 mice, diABZI STING agonist-1 ( 2.5 mg/kg ; subcutaneous injection ; 2.5 mg/kg ) activated secretion of IFNβ, IL-6, TNF, and CXCL1 in wild-type but not Sting −/− mice[1].

Chemical Properties

Molecular Weight	849.94
Formula	C₄₂H₅₁N₁₃O₇
Cas No.	2138299-33-7
Smiles	O=C(C1=CC(C)=NN1CC)N=C2N(C3=C(OC)C=C(C(N)=O)C=C3N2)C/C=C/CN4C5=C(OCCCN6CCOCC6)C=C(C(N)=O)C=C5NC4=NC(C7=CC(C)=NN7CC)=O
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (Insoluble)

DMSO: 80 mg/mL (94.12 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (3.88 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1766 mL	5.8828 mL	11.7655 mL	58.8277 mL
5 mM	0.2353 mL	1.1766 mL	2.3531 mL	11.7655 mL
10 mM	0.1177 mL	0.5883 mL	1.1766 mL	5.8828 mL
20 mM	0.0588 mL	0.2941 mL	0.5883 mL	2.9414 mL
50 mM	0.0235 mL	0.1177 mL	0.2353 mL	1.1766 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc