Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with favorable pharmacokinetic properties, exhibiting potency in suppressing IFN-α2B-induced STAT3 phosphorylation in Jurkat cells with an IC50 value of 17.2 nM [1].
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Description | JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with favorable pharmacokinetic properties, exhibiting potency in suppressing IFN-α2B-induced STAT3 phosphorylation in Jurkat cells with an IC50 value of 17.2 nM [1]. |
Molecular Weight | 420.46 |
Formula | C22H24N6O3 |
CAS No. | 2417134-93-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JAK-IN-26 2417134-93-9 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling Stem Cells JAK inhibitor inhibit