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V-0219 hydrochloride

🥰Excellent
Catalog No. T60047L
Alias V-0219 hydrochloride(878453-71-5 Free base)

V-0219 hydrochloride, an orally-active positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), is utilized in obesity-associated diabetes research.

V-0219 hydrochloride
Other Forms of V-0219 hydrochloride:

V-0219 hydrochloride

🥰Excellent
Purity: 99.97%
Catalog No. T60047LAlias V-0219 hydrochloride(878453-71-5 Free base)
V-0219 hydrochloride, an orally-active positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), is utilized in obesity-associated diabetes research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$32-In Stock
5 mg$76-In Stock
10 mg$130-In Stock
25 mg$248-In Stock
50 mg$369-In Stock
100 mg$526-In Stock
200 mg$708-In Stock
1 mL x 10 mM (in DMSO)$83-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.97%
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Product Introduction

Bioactivity
Description
V-0219 hydrochloride, an orally-active positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), is utilized in obesity-associated diabetes research.
SynonymsV-0219 hydrochloride(878453-71-5 Free base)
Chemical Properties
Molecular Weight446.89
FormulaC20H26ClF3N4O2
SmilesFC(F)(C1=CC=C(C2=NOC(CN3CCCC(CN4CCOCC4)C3)=N2)C=C1)F.Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (100.7 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.48 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2377 mL11.1884 mL22.3769 mL111.8844 mL
5 mM0.4475 mL2.2377 mL4.4754 mL22.3769 mL
10 mM0.2238 mL1.1188 mL2.2377 mL11.1884 mL
20 mM0.1119 mL0.5594 mL1.1188 mL5.5942 mL
50 mM0.0448 mL0.2238 mL0.4475 mL2.2377 mL
100 mM0.0224 mL0.1119 mL0.2238 mL1.1188 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

V-0219 HydrochlorideV0219 HydrochlorideV 0219 HydrochlorideGlucagonReceptorGlucagon ReceptorGLP-1878453-71-5 Free base878453-71-5
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