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AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $175 | In Stock | |
5 mg | $372 | In Stock | |
10 mg | $556 | In Stock | |
25 mg | $896 | In Stock | |
50 mg | $1,220 | In Stock | |
100 mg | $1,650 | In Stock | |
500 mg | $6,339 | In Stock | |
1 mL x 10 mM (in DMSO) | $397 | In Stock |
Description | AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM). |
Targets&IC50 | AAK1:2.2 nM |
In vitro | AAK1-IN-1can be used for neurodegenerative disease studies. Adaptor associated kinase 1 (AAK1) is a member of the Arkl/Prkl family of serine/threonine kinases and modulates clatherin coated endocytosis. and receptor-mediated endocytosis[1]. |
Alias | LX-9211 |
Molecular Weight | 385.4 |
Formula | C19H23F4N3O |
Cas No. | 1815613-42-3 |
Smiles | CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(c1)C(F)F |
Relative Density. | 1.188 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 220 mg/mL (570.84 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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