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Decanoic Acid

Name: Decanoic Acid
Brand: TargetMol
SKU: T3379
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3379Cas No. 334-48-5

Alias Decoic acid, Caprynic acid, CAPRIC ACID

Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.

Decanoic Acid

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Purity: 98.59%

Catalog No. T3379Alias Decoic acid, Caprynic acid, CAPRIC ACIDCas No. 334-48-5

Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$31	In Stock	In Stock
1 g	$40	In Stock	In Stock
2 g	$56	-	In Stock
5 g	$92	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$35	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.59%

Appearance:Viscous

Color:White

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COA HPLC HNMR LCMS

Product Introduction

Decanoic Acid AI Summary

Decanoic Acid is a versatile bioactive molecule exhibiting a wide range of biological activities. It notably inhibits Bacillus subtilis spore germination with an IC50 value of approximately 6030000 nM and shows antibacterial action against Staphylococcus aureus with a MIC of 250.0 μg/mL, though it is less effective against methicillin-resistant strains. The compound also demonstrates antioxidant properties, with a deltaA value of 0.51 in an MTT assay. In enzymatic assays, Decanoic Acid shows activity in the human recombinant enzyme UGT1A3 and moderate activity in UGT1A8, with 80.0 and 19.0 pm/min/mg, respectively. It was ineffective against UGT1A10. Additionally, it displays phytotoxic actions, causing 80.0% mortality in Echinochloa crus-galli (barnyard grass) at 5 mg/mL. Moreover, Decanoic Acid possesses nematicidal activities against Meloidogyne incognita and Bursaphelenchus xylophilus, exhibiting varied mortality rates based on concentration and exposure time. Its capacity to inhibit human tyrosyl-DNA phosphodiesterase 1 (TDP1) and modulate several signal pathways, including peroxisome proliferator-activated receptor gamma and glucocorticoid receptor pathways, underlines its potent, multifaceted nature. For human receptors, Decanoic Acid acts as an agonist for GPR84 and PPAR receptors, displaying moderate potency with IC50 values in the range of 30000.0 nM. It also serves as an antagonist for ROR-gamma and induces DNA re-replication in MCF 10a cells. Additionally, it exhibits partial agonist activity at human PPARG with an EC50 of 7600.0 nM. Lastly, the compound inhibits electric eel acetylcholinesterase and equine serum butyrylcholinesterase by 15.74% and 9.91%, respectively, at 10 M and exhibits a moderate cytostatic effect on human MONO-MAC-6 cells with an IC50 value exceeding 200000.0 nM. With a partition coefficient (logP) of 3.92, a dissociation constant (pKa) of 4.9, and a logD7.2 value of 1.62, Decanoic Acid demonstrates multifaceted bioactivity suitable for various potential therapeutic applications..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.
Synonyms	Decoic acid, Caprynic acid, CAPRIC ACID

Chemical Properties

Molecular Weight	172.26
Formula	C₁₀H₂₀O₂
Cas No.	334-48-5
Smiles	CCCCCCCCCC(O)=O
Relative Density.	0.893 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (1451.29 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (11.61 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.8052 mL	29.0259 mL	58.0518 mL	290.2589 mL
5 mM	1.1610 mL	5.8052 mL	11.6104 mL	58.0518 mL
10 mM	0.5805 mL	2.9026 mL	5.8052 mL	29.0259 mL
20 mM	0.2903 mL	1.4513 mL	2.9026 mL	14.5129 mL
50 mM	0.1161 mL	0.5805 mL	1.1610 mL	5.8052 mL
100 mM	0.0581 mL	0.2903 mL	0.5805 mL	2.9026 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc