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Angeli's Salt

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Catalog No. T36177Cas No. 13826-64-7
Alias Sodium α-oxyhyponitrite, Angeli's Salt

Angeli's salt is regarded as a classical nitroxyl (NO-) donor, but under certain conditions evolution of NO is also observed.1 It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2.3 minutes at 37°C (pH 7.4) to liberate 0.54 moles of NO per mole of parent compound.[1],[2]

Angeli's Salt

Angeli's Salt

😃Good
Catalog No. T36177Alias Sodium α-oxyhyponitrite, Angeli's SaltCas No. 13826-64-7
Angeli's salt is regarded as a classical nitroxyl (NO-) donor, but under certain conditions evolution of NO is also observed.1 It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2.3 minutes at 37°C (pH 7.4) to liberate 0.54 moles of NO per mole of parent compound.[1],[2]
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$10835 days35 days
10 mg$19835 days35 days
50 mg$81635 days35 days
100 mg$1,42035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Angeli's salt is regarded as a classical nitroxyl (NO-) donor, but under certain conditions evolution of NO is also observed.1 It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2.3 minutes at 37°C (pH 7.4) to liberate 0.54 moles of NO per mole of parent compound.[1],[2]
SynonymsSodium α-oxyhyponitrite, Angeli's Salt
Chemical Properties
Molecular Weight101.017
FormulaH2N2NaO3
Cas No.13826-64-7
Smiles[Na].ONN(=O)=OjcExt:v:0:0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 50 mg/mL (494.97 mM), Sonication is recommended.
PBS (pH 7.2): 50 mg/mL (494.97 mM), Sonication is recommended.
Solution Preparation Table
H2O/PBS (pH 7.2)
1mg5mg10mg50mg
1 mM9.8993 mL49.4966 mL98.9932 mL494.9662 mL
5 mM1.9799 mL9.8993 mL19.7986 mL98.9932 mL
10 mM0.9899 mL4.9497 mL9.8993 mL49.4966 mL
20 mM0.4950 mL2.4748 mL4.9497 mL24.7483 mL
50 mM0.1980 mL0.9899 mL1.9799 mL9.8993 mL
100 mM0.0990 mL0.4950 mL0.9899 mL4.9497 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Sodium a-oxyhyponitriteSodium alpha-oxyhyponitrite
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