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Anti-SOST Antibody (4D453) (Synonyms: VBCH, SOST1, sclerostin, DAND6, CDD)

Catalog No. TMAY-00998 Copy Product Info
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Anti-SOST Antibody (4D453) is a Mouse antibody targeting SOST. Anti-SOST Antibody (4D453) can be used in ELISA.

Anti-SOST Antibody (4D453)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00998
Synonyms VBCH, SOST1, sclerostin, DAND6, CDD

Anti-SOST Antibody (4D453) is a Mouse antibody targeting SOST. Anti-SOST Antibody (4D453) can be used in ELISA.

Anti-SOST Antibody
(4D453)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SOST Antibody (4D453) is a Mouse antibody targeting SOST. Anti-SOST Antibody (4D453) can be used in ELISA.
SynonymsVBCH, SOST1, sclerostin, DAND6, CDD
Ig Type
Mouse IgG1
Clone
4D453
Reactivity
Human
Specificity
Human SOST/Sclerostin
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SOST (rhSOST; TMPY-00925; NP_079513.1; Gln 24-Tyr 213). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteeoblasts differentiated for 21 days, and was originally identified as an important regulator of bone remodeling, homeostasis, and links bone resorption and bone apposition. Recent studies have revealed that Sclerostin protein inhibits the bone growth probably by binding to the extracellular domain of the Wnt coreceptors LRP5 and LRP6 and disrupting Wnt-induced Frizzled-LRP complex formation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human SOST protein ( Catalog#10593-H07H)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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