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Enfumafungin

🥰Excellent
Catalog No. T75686Cas No. 260979-95-1

Enfumafungin is a triterpenoid glycoside isolated from endophytic fungi, exhibiting antifungal activity against Candida and Aspergillus species by inhibiting (1,3)-β-D-glucan synthesis.

Enfumafungin

Enfumafungin

🥰Excellent
Catalog No. T75686Cas No. 260979-95-1
Enfumafungin is a triterpenoid glycoside isolated from endophytic fungi, exhibiting antifungal activity against Candida and Aspergillus species by inhibiting (1,3)-β-D-glucan synthesis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$78In StockIn Stock
5 mg$340In StockIn Stock
10 mg$597-In Stock
1 mL x 10 mM (in DMSO)$560-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Enfumafungin is a triterpenoid glycoside isolated from endophytic fungi, exhibiting antifungal activity against Candida and Aspergillus species by inhibiting (1,3)-β-D-glucan synthesis.
In vitro
Enfumafungin (24-48 hours) inhibits the growth of Candida and Aspergillus with MIC values both below 0.5 μg/mL[1].
In vivo
Enfumafungin (50–200 mg/kg), administered via intraperitoneal injection twice daily for 2 days, significantly reduced the colony-forming units (CFU) of C. albicans in the kidneys of mice, with an ED90 of 90 mg/kg.
Chemical Properties
Molecular Weight708.88
FormulaC38H60O12
Cas No.260979-95-1
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (112.85 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (4.66 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4107 mL7.0534 mL14.1068 mL70.5338 mL
5 mM0.2821 mL1.4107 mL2.8214 mL14.1068 mL
10 mM0.1411 mL0.7053 mL1.4107 mL7.0534 mL
20 mM0.0705 mL0.3527 mL0.7053 mL3.5267 mL
50 mM0.0282 mL0.1411 mL0.2821 mL1.4107 mL
100 mM0.0141 mL0.0705 mL0.1411 mL0.7053 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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