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Formate dehydrogenase
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Catalog No. T76149 Copy Product Info
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Formate dehydrogenase is an enzyme widely found in both prokaryotes and eukaryotes that catalyzes the interconversion of formate and CO₂, accompanied by redox reactions involving the coenzymes NAD⁺/NADH or other electron carriers. Formate dehydrogenase can be used for NAD(P)H coenzyme regeneration, CO₂ fixation and conversion, biosensors, and industrial biocatalysis.
Formate dehydrogenase
Cas No. 9028-85-7
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $75 | - | In Stock | |
| 5 mg | $193 | - | In Stock | |
| 10 mg | $290 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Formate dehydrogenase is an enzyme widely found in both prokaryotes and eukaryotes that catalyzes the interconversion of formate and CO₂, accompanied by redox reactions involving the coenzymes NAD⁺/NADH or other electron carriers. Formate dehydrogenase can be used for NAD(P)H coenzyme regeneration, CO₂ fixation and conversion, biosensors, and industrial biocatalysis. |
| In vitro | Overexpression of Formate dehydrogenase (1 g/L formate; 48–96 h) in S. cerevisiae FA enhances the strain’s tolerance to 1 g/L formate, allowing it to break down formate into CO₂, while simultaneously increasing glucose utilization, cell density, and cell viability [1]. Overexpression of Formate dehydrogenase (4 g/L acetic acid; 48–96 h) in S. cerevisiae FA increases the strain’s tolerance to acetic acid. By converting CO₂ into formate and generating additional ATP, it enables faster glucose utilization, higher ethanol yield, higher cell density, and greater cell viability [1]. |
| Cas No. | 9028-85-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Related Tags: Formate dehydrogenase in vitro
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