Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

Thalidomide 4-fluoride

🥰Excellent
Catalog No. T7755Cas No. 835616-60-9
Alias E3 ligase Ligand 4

Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.

Thalidomide 4-fluoride
Other Forms of Thalidomide 4-fluoride:

Thalidomide 4-fluoride

🥰Excellent
Purity: 99.12%
Catalog No. T7755Alias E3 ligase Ligand 4Cas No. 835616-60-9
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 mg$29In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.12%
Contact us for more batch information

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity
Description
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
SynonymsE3 ligase Ligand 4
Chemical Properties
Molecular Weight276.22
FormulaC13H9FN2O4
Cas No.835616-60-9
SmilesO=C1N(C(=O)C=2C1=CC=CC2F)C3C(=O)NC(=O)CC3
Relative Density.1.570 g/cm3 (Predicted)
ColorWhite
Appearancesolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 199 mg/mL (720.44 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6203 mL18.1015 mL36.2030 mL181.0151 mL
5 mM0.7241 mL3.6203 mL7.2406 mL36.2030 mL
10 mM0.3620 mL1.8102 mL3.6203 mL18.1015 mL
20 mM0.1810 mL0.9051 mL1.8102 mL9.0508 mL
50 mM0.0724 mL0.3620 mL0.7241 mL3.6203 mL
100 mM0.0362 mL0.1810 mL0.3620 mL1.8102 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Thalidomide 4-fluorideThalidomide 4fluorideThalidomide 4 fluorideThalidomideLigands for E3 LigaseLigandforE3LigaseLigand for E3 LigaseIRAK4InhibitorinhibitE3 ligase-recruiting MoietyCereblon ligand-4Cereblon ligand4Cereblon ligand 4
Related Tags: buy Thalidomide 4-fluoride | purchase Thalidomide 4-fluoride | Thalidomide 4-fluoride cost | order Thalidomide 4-fluoride | Thalidomide 4-fluoride chemical structure | Thalidomide 4-fluoride formula | Thalidomide 4-fluoride molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.